Table 1.
Clinical Characteristics of AP Patients in the Older Group and Oldest Group
| All Patients (n=473) | Older Group (60–80 Years) (n=393) | Oldest Group (≥80years) (n=80) | P | |
|---|---|---|---|---|
| Age (years) | 70.5±7.7 | 67.8±5.3 | 83.5±2.8 | 0.001 |
| Sex | ||||
| Male | 217 (45.9%) | 180 (45.8%) | 37 (46.3%) | 0.942 |
| Female | 256 (54.1%) | 213 (54.2%) | 43 (53.8%) | |
| BMI | 22.19±2.85 | 22.36±2.89 | 21.07±3.18 | 0.001 |
| Severity of AP | ||||
| MAP | 150 (31.7%) | 119 (30.3%) | 31 (38.8%) | 0.312 |
| MSAP | 190 (40.2%) | 160 (40.7%) | 30 (37.5%) | |
| SAP | 133 (28.1%) | 114 (29.0%) | 19 (23.8%) | |
| Aetiology of AP | ||||
| Biliary | 384 (81.2%) | 313 (79.6%) | 71 (88.6%) | 0.203 |
| HTG | 17 (3.6%) | 16 (4.1%) | 1 (1.3%) | |
| Alcohol | 20 (4.2%) | 19 (4.8%) | 1 (1.3%) | |
| Other | 52 (11.0%) | 45 (11.5%) | 7 (8.8%) | |
| Hypertension | ||||
| Yes | 169 (35.7%) | 134 (34.1%) | 35 (43.8%) | 0.101 |
| No | 304 (64.3%) | 259 (65.9%) | 45 (56.3%) | |
| Diabetes | ||||
| Yes | 37 (7.8%) | 31 (92.1%) | 6 (7.5%) | 0.906 |
| No | 436 (92.2%) | 362 (92.1%) | 74 (92.5%) | |
| Chronic renal failure | ||||
| Yes | 11 (2.3%) | 10 (2.5%) | 79 (98.8%) | 0.484 |
| No | 462 (97.7%) | 383 (97.5%) | 1 (1.3%) | |
| Smoking | ||||
| Yes | 101 (21.4%) | 90 (22.9%) | 11 (13.8%) | 0.069 |
| No | 372 (78.6%) | 303 (77.1%) | 69 (86.3%) | |
| Drinking | ||||
| Yes | 84 (17.8%) | 73 (18.6%) | 11 (13.8%) | 0.303 |
| No | 389 (82.2%) | 320 (81.4%) | 69 (86.3%) | |
| Complications | ||||
| Organ failure | ||||
| Acute respiratory failure | 120 (25.4%) | 102 (26.0%) | 18 (22.5%) | 0.517 |
| Acute renal failure | 57 (12.1%) | 44 (11.2%) | 13 (16.3%) | 0.206 |
| Shock | 23 (4.9%) | 22 (5.6%) | 1 (1.3%) | 0.099 |
| Multi-organ failure | 45 (9.5%) | 35 (8.9%) | 10 (12.5%) | 0.318 |
| Pancreatic complications | ||||
| ANC | 31 (6.6%) | 26 (6.6%) | 5 (6.3%) | 0.073 |
| ANC infection | 28 (5.9%) | 26 (6.6%) | 2 (2.5%) | |
| APFC | 123 (26.0%) | 108 (27.5%) | 15 (18.8%) | |
| APFC infection | 14 (3.0%) | 13 (3.3%) | 1 (1.3%) | |
| WON | 6 (1.3%) | 4 (1.3%) | 2 (2.5%) | |
| WON infection | 4 (0.8%) | 2 (0.5%) | 2 (2.5%) | |
| PPC | 2 (0.4%) | 1 (0.3%) | 1 (1.3%) | |
| Operative treatment | ||||
| ERCP | 103 (21.8%) | 81 (20.6%) | 22 (27.5%) | 0.174 |
| PCD | 117 (24.7%) | 93 (23.7%) | 24 (30.0%) | 0.231 |
| Cholecystectomy | 19 (4.0%) | 19 (4.8%) | 0 (0.0%) | 0.097 |
| Necrosectomy | 32 (6.8%) | 28 (7.1%) | 4 (5.0%) | 0.097 |
| Symptoms | ||||
| Abdominal pain | 278 (58.8%) | 241 (61.3%) | 37 (46.3%) | 0.013 |
| Vomiting | 34 (7.2%) | 26 (6.6%) | 8 (10%) | 0.285 |
| Jaundice | 49 (10.4%) | 35 (8.9%) | 14 (17.5%) | 0.021 |
| Dyspnoea | 66 (14.0%) | 45 (11.5%) | 21 (26.3%) | 0.001 |
| ICU admission | ||||
| Yes | 159 (33.6%) | 129 (32.8%) | 30 (37.5%) | 0.42 |
| No | 314 (66.4%) | 264 (67.2%) | 50 (62.5%) | |
| LOS, days | 12.1±10.4 | 11.5±10.2 | 15.3±11.0 | 0.003 |
| Death | ||||
| Yes | 48 (10.1%) | 35 (8.9%) | 13 (16.3%) | 0.047 |
| No | 425 (89.9%) | 358 (91.1%) | 67 (83.8%) |
Notes: Continuous variables are presented as the mean (standard deviation). Categorical variables are presented as number (percentage).
Abbreviations: AP, acute pancreatitis; ARF, acute respiratory failure; LOS, length of stay; ERCP, endoscopic retrograde cholangiopancreatography; ICU, intensive care unit; BMI, body mass index; AKI, acute kidney injury; MAP, mild acute pancreatitis; MSAP, moderately severe acute pancreatitis; SAP, severe acute pancreatitis; HTG, hypertriglyceridemia; ERCP, endoscopic retrograde cholangiopancreatography; PPC, pancreatic pseudocyst; WON, walled-off necrosis; APFC, acute peripancreatic fluid collection; ANC, acute necrosis collection; PCD, percutaneous drainage; HTG, hypertriglyceridemia.