Table 3.
Univariate and Multivariate Analyses of Risk Factors for Mortality in Ageing Patients with Acute Pancreatitis
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Age (years) | 1.06 (1.02–1.10) | 0.003 | 3.30 (1.32–8.27) | 0.011 |
| Sex (male/female) | 1.06 (1.02–1.10) | 0.546 | ||
| BMI | 1.03 (0.94–1.14) | 0.512 | ||
| Severity of AP | ||||
| MAP | Ref (1.00) | Ref (1.00) | ||
| MSAP | 2.72 (0.74–10.08) | 0.134 | 1.58 (0.35–7.18) | 0.546 |
| SAP | 17.50 (5.24–58.48) | 0.001 | 2.37 (0.45–12.43) | 0.307 |
| Aetiology of AP | ||||
| Biliary | Ref (1.00) | |||
| HTG | 0.55 (0.07–4.28) | 0.570 | ||
| Alcohol | 1.56 (0.44–5.57) | 0.492 | ||
| Other | 0.94 (0.35–2.51) | 0.903 | ||
| Hypertension | 1.32 (0.72–2.43) | 0.366 | ||
| Diabetes | 0.48 (0.11–2.08) | 0.330 | ||
| Chronic renal failure | 0.88 (0.11–7.05) | 0.907 | ||
| History of smoking | 1.11 (0.54–2.26) | 0.780 | ||
| History of drinking | 1.43 (0.70–2.94) | 0.326 | ||
| Symptoms | ||||
| Abdominal pain | 1.31 (0.71–2.45) | 0.389 | ||
| Vomiting | 1.35 (0.68–2.71) | 0.394 | ||
| Jaundice | 1.27 (0.52–3.16) | 0.608 | ||
| Dyspnoea | 1.27 (0.56–2.84) | 0.568 | ||
| Operative treatment | ||||
| ERCP | 0.22 (0.56–2.84) | 0.012 | 0.28 (0.07–1.12) | 0.072 |
| PCD | 1.15 (0.58–2.25) | 0.691 | ||
| Cholecystectomy | 0.00 (0.00-) | 0.998 | ||
| Necrosectomy | 1.29 (0.43–3.85) | 0.649 | ||
| Organ failure | ||||
| Acute respiratory failure | 13.86 (6.78–28.32) | 0.001 | 4.23 (1.32–13.50) | 0.015 |
| Acute renal failure | 15.02 (7.65–29.51) | 0.001 | 0.94 (0.27–3.36) | 0.927 |
| Shock | 23.69 (9.36–59.95) | 0.001 | 4.95 (1.58–15.57) | 0.006 |
| Multi-organ failure | 22.01 (10.69–45.34) | 0.001 | 4.61 (1.39–15.34) | 0.013 |
| Local complication | ||||
| ANC | 5.80 (2.22–15.12) | 0.001 | 0.87 (0.23–3.28) | 0.837 |
| ANC infection | 9.26 (3.65–23.52) | 0.001 | 0.88 (0.31–2.49) | 0.812 |
| APFC | 1.80 (0.82–3.98) | 0.145 | 0.46 (0.04–5.33) | 0.532 |
| APFC infection | 1.28 (0.16–10.47) | 0.817 | 1.35 (0.36–5.04) | 0.655 |
| WON | 3.33 (0.37–30.37) | 0.285 | 1.26 (0.09–17.77) | 0.865 |
| WON infection | 5.56 (0.55–56.67) | 0.148 | 6.70 (0.50–89.74) | 0.151 |
| PPC | 0.00 (0.00-) | 0.99 | 0.00 (0.00-) | 0.999 |
Abbreviations: AP, acute pancreatitis; ARF, acute respiratory failure; LOS, length of stay; ERCP, endoscopic retrograde cholangiopancreatography; ICU, intensive care unit; BMI, body mass index; AKI, acute kidney injury; MAP, mild acute pancreatitis; MSAP, moderately severe acute pancreatitis; SAP, severe acute pancreatitis; OR, odds ratio; ERCP, endoscopic retrograde cholangiopancreatography; PPC, pancreatic pseudocyst; WON, walled-off necrosis; APFC, acute peripancreatic fluid collection; ANC, acute necrosis collection; PCD, percutaneous drainage; HTG, hypertriglyceridemia.