Table 3.
Comparison between baseline characteristics of SVR vs Non-SVR patients.
| Parameter | Non-SVR12 (N = 76) | SVR12 (N = 1,312) | P value |
|---|---|---|---|
| Age (y), M ± SD | 58.62 ± 16.8 | 45.80 ± 12.7 | <0.001 |
| Age group | |||
| 18–59 n (%) | 37 (49) | 1,090 (83) | |
| ≥60 n (%) | 39 (51) | 222 (17) | |
| Gender | |||
| Male, n (%) | 30 (39.5) | 626 (47.7) | |
| Female, n (%) | 46 (60.5) | 686 (52.3) | |
| BMI (kg/m2), M ± SD | 27.63 ± 4.7 | 28.08 ± 5.9 | |
| BMI | |||
| <30, n (%) | 54 (71) | 950 (72) | |
| >30, n (%) | 22 (29) | 362 (28) | |
| Treatment status | |||
| Naive, n (%) | 30 (39.5) | 973 (74) | |
| Experienced, n (%) | 46 (60.5) | 339 (26) | |
| Treatment arm | 0.04 | ||
| SOF/DCV, n (%) | 54 (71) | 918 (70) | |
| SOF/VEL, n (%) | 22 (29) | 394 (30) | |
| Cirrhosis | |||
| Present, n (%) | 10 (24) | 60 (4.5) | |
| Absent, n (%) | 32 (76) | 1,286 (96) | |
|
Comorbidities Diabetes, n (%) |
23 (30) | 80 (6) | |
| Obesity, n (%) | 23 (30.3) | 85 (6.5) | |
| Hypertension, n (%) | 58 (76) | 144 (11) | |
| HBsAg, n (%) | 1 (1.3) | 17 (1.3) | <0.001 |
|
Risk factors Tobacco smoking, n (%) |
32 (42) | 374 (29) | |
| Surgery, n (%) | 22 (29) | 82 (6) | |
| Blood transfusion, n (%) | 46 (60.6) | 319 (24) | |
|
Laboratory data HB (g/dl) M ± SD |
13.03 ± 1.9 | 12.98 ± 2.2 | |
| WBCs (×109/L) M ± SD | 7.04 ± 2.0 | 7.62 ± 2.3 | 0.03 |
| PLT (×109/L) M ± SD | 208.9 ± 81 | 226.9 ± 102 | |
| AST (ULN: 40 U/L) M ± SD | 69.2 ± 35 | 72.2 ± 36 | |
| ALT (ULN: 40 U/L) M ± SD | 87.9 ± 67 | 70.9 ± 63 | 0.03 |
| Albumin (g/L) M ± SD | 39.7 ± 6 | 40.3 ± 9 | |
| Creatinine (mg/dl) M ± SD | 99.9 ± 25 | 98.5 ± 40 | |
| INR M ± SD | 1.3 ± 0.1 | 1.2 ± 0.1 | |
| TBR (μmol/L) M ± SD | 10.8 ± 5 | 11.4 ± 6 | |
| HCV PCR log10 | 6.2 ± 3 | 6.1 ± 4 | <0.001 |
Bold values represent statistical significance.