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. Author manuscript; available in PMC: 2020 Sep 16.
Published in final edited form as: J Neural Eng. 2017 Dec 8;15(3):036018. doi: 10.1088/1741-2552/aaa039

Figure 7.

Figure 7.

Plot shows compositional analysis with angular (arcsin) transformations of proportional make-up in specific cytokine levels at 90 min post-LPS injection. Acute subjects showed a decrease in TNF-α proportion (h > 0.4) and a small (h < 0.25) but significant increase in IL-10 proportion due to stimulation, indicating strong inflammatory modulation due to stimulation. Chronic subjects showed no significant modulation in proportion levels due to stimulation in any of the three cytokines, consistent with compromised vagus function after chronic cervical cuffing. Error bars, s.e.m. *P < 0.05.