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Over-expression of RIG-I in human THP1-induced macrophages has no effects on cell death in normal hepatocytes. The conditioned medium from RIG-I lentivirus-infected THP-1-derived macrophages or control lentivirus-infected THP-1-derived macrophages to culture the normal human hepatocytes L02 cells. Cell death of RIG-I lentivirus-infected macrophages, control lentivirus-infected macrophages and untreated control L02 cells were tested by FACS assay with PI staining.
