Table 4.
Prevalence of noncardiovascular co-morbidities for women with congenital heart defects (CHD) by pregnancy during project period, pooled across and by 3 surveillance sites, 2008 to 2010**
| Overall n = 26,655 | EU* n = 1,994 | MA n = 23,203 | NY* n = 1,458 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pregnant n = 5,672 (21.3%) | Not Pregnant n = 20,983 (21.3%) | p_value | Pregnant n = 275 (13.8%) | Not Pregnant n = 1,192 (86.2%) | p_value | Pregnant n = 5,211 (22.5%) | Not Pregnant n = 17,992 (21.3%) | p_value | Pregnant n = 186 (12.8%) | Not Pregnant n = 1,272 (87.2%) | p_value | |
| Diabetes Mellitus | 23.6% | 17.2% | <0.001 | 6.9% | 3.0% | 0.001 | 25.3% | 19.3% | <0.001 | <10 | 5.5% | ns |
| Other Endocrine | 16.5% | 12.0% | <0.001 | 6.2% | 4.0% | Ns | 17.5% | 13.1% | <0.001 | <10 | 6.5% | ns |
| Birth Defects | 20.4% | 15.8% | <0.001 | 8.7% | 12.3% | Ns | 21.5% | 16.1% | <0.001 | 5.9% | 15.3% | 0.001 |
| Hematologic | 22.5% | 17.6% | <0.001 | 27.3% | 10.7% | <0.001 | 22.2% | 18.7% | <0.001 | 24.7% | 12.0% | <0.001 |
| Neoplasms | 18.8% | 14.6% | <0.001 | 21.5% | 6.5% | <0.001 | 19.1% | 15.9% | <0.001 | <10 | 7.2% | ns |
| Gastrological | 36.4% | 31.3% | <0.001 | 33.8% | 15.3% | <0.001 | 36.7% | 33.2% | <0.001 | 31.7% | 25.2% | ns |
| Other Genitourinary | 7.7% | 9.3% | <0.001 | 6.2% | 2.8% | 0.01 | 7.9% | 10.4% | <0.001 | <10 | 3.8% | ns |
| CNS | 12.6% | 13.3% | ns | 5.5% | 5.0% | ns | 13.3% | 14.7% | 0.01 | 5.9% | 5.8% | ns |
| Immunologic/Rheumatologic/Allergy | 3.3% | 3.5% | ns | 3.6% | 1.5% | 0.01 | 3.4% | 3.7% | ns | <10 | 2.9% | ns |
| Respiratory/Pulmonary | 40.5% | 38.2% | 0.01 | 38.6% | 25.5% | <0.001 | 40.9% | 40.1% | ns | 30.7% | 29.3% | ns |
| Musculoskeletal | 43.6% | 36.4% | <0.001 | 28.4% | 14.5% | <0.001 | 44.9% | 39.6% | ns | 26.9% | 20.4% | 0.05 |
| Injury/Trauma | 16.9 % | 15.9% | ns | 17.5% | 8.0% | <0.001 | 16.5% | 16.1% | ns | 25.8% | 23.5% | ns |
| Infectious Disease | 29.7% | 21.8% | <0.001 | 45.5% | 17.9% | <0.001 | 28.6% | 21.6% | <0.001 | 37.1% | 30.4% | ns |
| Mental Health | 42.7% | 33.9% | <0.001 | 22.2% | 10.8% | <0.001 | 44.3% | 37.0% | <0.001 | 30.7% | 20.2% | 0.001 |
| Genitourinary / Gynecological | 38.7% | 29.4% | <0.001 | 78.9% | 16.1% | <0.001 | 36.2% | 31.4% | <0.001 | 48.9% | 18.7% | <0.001 |
CHD = Congenital Heart Defect.
*
EU=Emory University; catchment area incl. 5 metro-Atlanta counties: Clayton, Cobb, DeKalb, Fulton and Gwinnett; MA=Massachusetts Dept. of Public Health; catchment area is state-wide; and NY=New York State Dept. of Health; catchment area incl. 11 counties: Allegany, Bronx, Cattaraugus, Chautauqua, Erie, Genesee, Monroe, Niagara, Orleans, Westchester &Wyoming.
**
Data collapsed across CHD severity.
^^
Individuals classified with ICD-9_CM code 745.5 in isolation are not included.