Table 1.
Type of 3D Bioprinting technology | Basic Principle Involved | Applications | Advantages | Disadvantages |
---|---|---|---|---|
Laser-Assisted Printing |
Laser pulse stimulates a small area of the target. | Bone tissue engineering Creation of complex scaffolds for guided tissue regeneration. | High degree of precision and resolution, ability to use high viscosity bio-ink print high cell density >95% cell viability |
Time consuming, high cost |
Ink-jet Printing | Pressure change in the upstream of nozzle Results in a downstream droplet ejection. | Printing of complex ceramic-like structures to support guided tissue regeneration. Drop-by-drop bioprinting of live cells for cell aggregate approach. |
High speed, availability, low cost >85% cell viability |
Lack of precision in droplet placement and size, need for low viscosity bio-ink |
Extrusion based printing | Material fuses together at room temperature after leaving the nozzle. | Can be used with many material for creation of simple biocompatible biodegradable scaffolds for guided tissue regeneration | Affordability, high-speed printing, and potential of printing multiple materials at the same time | Only thermoplastic materials can be used Inability to embed cells in the material |
Multi head deposition system | Extrusion of components via multiple mixing nozzles, exposing each layer to UV light or heat | Can be used with wider range and forms of material for creation of biocompatible and biodegradable scaffolds for guided tissue regeneration | Wide range of flexibility in the material that can be used | Subdued resolution and speed |