Table 2.
Case reports of auditory involvement associated with thiamine deficiency
| Author | Age/sex | Presumed aetiology | MRI findings | Auditory symptom recovery |
| Kondo et al16 | 28/F | Cancer-induced dietary limitations, 5-FU, and parenteral nutrition | Not reported | Yes |
| Towbin et al17 | 15/F | Gastric bypass | CT—non-specific findings. MRI not done | Yes |
| Walker et al18 | 17/F | Hyperemesis gravidarum | Bilateral hyperintensities of medial thalami and posterior limb of internal capsule | Yes |
| Foster et al19 | 35/F | Gastric bypass | Bilateral hyperintensities of floor of the fourth ventricle, periaqueductal grey matter, the medial thalami, and the premotor and motor cortices | Not mentioned |
| Wilson et al20 | 17/F | Hyperemesis gravidarum | Bilateral medial thalamic signal hyperintensities | Partial |
| Flabeau et al*14 | 31/F | Crohn’s disease/parenteral nutrition | Signal changes in inferior colliculi | Yes |
| Jethava et al21 | 35/F | Gastric bypass | Bilateral symmetric intraparenchymal thalami signal changes | Partial |
| Scarano et al22 | 27/F | Sleeve gastrectomy | Signal hyperintensities of the thalamus, periaqueductal grey matter, mammillary body and caudate nucleus | Not mentioned |
| Zhang et al23 | 23/M | Pancreatitis—diet limitation | Symmetric hyperintensities in the bilateral inferior colliculi, posteromedial thalamus, mammillary bodies and cerebellar peduncles | Partial |
| Lamdhade et al15 | 16/F | Failure to thrive from intestinal atresia | Hyperintense signal changes in the bilateral caudate nucleus, mammillary body, periaqueductal region and vermis | No |
| Wu et al24 | 57/M | Anorexia | Bilateral signal hyperintensities in the thalamus, periaqueductal grey matter, and the structures surrounding the third and the fourth ventricles | Yes |
| Moussa et al25 | 49/M | Antral gastritis | Signal hyperintensities in the vermis, bilateral inferior colliculi, dorsomedial thalamus, posterior part of corpus callosum and bilateral inferior cerebellar peduncles | Yes |
| Hansen et al†26 | 43/F | Alcoholism and nutritional | Hyperintensities in the bilateral thalamus, periaqueductal grey matter and the floor of fourth ventricle | Partial |
| Nakamura et al†27 | 61/M | Unclear | Symmetrical high signal intensities involving the tectum, bilateral inferior colliculi and the medial thalami | Yes |
| Gilani et al†28 | 35/F | Gastric bypass | Hyperintense signal changes in the medial thalami, hypothalami, mammillary bodies and periaqueductal grey matter | Partial |
| Nguyen et al29 | 35/F | Sleeve gastrectomy | Signal hyperintensities in the mammillary bodies bilaterally, the periaqueductal grey matter and the inferior colliculus | Yes |
| Prosperini et al13 | 27/M | Sleeve gastrectomy | Symmetric hyperintensities in the bilateral thalamus, hypothalamus and mammillary bodies | Yes |
*Image publication.
†Abstract only.
F, female; 5-FU, 5-fluorouracil; M, male.