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. 2020 Sep 15;13(9):e233144. doi: 10.1136/bcr-2019-233144

Table 2.

Case reports of auditory involvement associated with thiamine deficiency

Author Age/sex Presumed aetiology MRI findings Auditory symptom recovery
Kondo et al16 28/F Cancer-induced dietary limitations, 5-FU, and parenteral nutrition Not reported Yes
Towbin et al17 15/F Gastric bypass CT—non-specific findings. MRI not done Yes
Walker et al18 17/F Hyperemesis gravidarum Bilateral hyperintensities of medial thalami and posterior limb of internal capsule Yes
Foster et al19 35/F Gastric bypass Bilateral hyperintensities of floor of the fourth ventricle, periaqueductal grey matter, the medial thalami, and the premotor and motor cortices Not mentioned
Wilson et al20 17/F Hyperemesis gravidarum Bilateral medial thalamic signal hyperintensities Partial
Flabeau et al*14 31/F Crohn’s disease/parenteral nutrition Signal changes in inferior colliculi Yes
Jethava et al21 35/F Gastric bypass Bilateral symmetric intraparenchymal thalami signal changes Partial
Scarano et al22 27/F Sleeve gastrectomy Signal hyperintensities of the thalamus, periaqueductal grey matter, mammillary body and caudate nucleus Not mentioned
Zhang et al23 23/M Pancreatitis—diet limitation Symmetric hyperintensities in the bilateral inferior colliculi, posteromedial thalamus, mammillary bodies and cerebellar peduncles Partial
Lamdhade et al15 16/F Failure to thrive from intestinal atresia Hyperintense signal changes in the bilateral caudate nucleus, mammillary body, periaqueductal region and vermis No
Wu et al24 57/M Anorexia Bilateral signal hyperintensities in the thalamus, periaqueductal grey matter, and the structures surrounding the third and the fourth ventricles Yes
Moussa et al25 49/M Antral gastritis Signal hyperintensities in the vermis, bilateral inferior colliculi, dorsomedial thalamus, posterior part of corpus callosum and bilateral inferior cerebellar peduncles Yes
Hansen et al26 43/F Alcoholism and nutritional Hyperintensities in the bilateral thalamus, periaqueductal grey matter and the floor of fourth ventricle Partial
Nakamura et al27 61/M Unclear Symmetrical high signal intensities involving the tectum, bilateral inferior colliculi and the medial thalami Yes
Gilani et al28 35/F Gastric bypass Hyperintense signal changes in the medial thalami, hypothalami, mammillary bodies and periaqueductal grey matter Partial
Nguyen et al29 35/F Sleeve gastrectomy Signal hyperintensities in the mammillary bodies bilaterally, the periaqueductal grey matter and the inferior colliculus Yes
Prosperini et al13 27/M Sleeve gastrectomy Symmetric hyperintensities in the bilateral thalamus, hypothalamus and mammillary bodies Yes

*Image publication.

†Abstract only.

F, female; 5-FU, 5-fluorouracil; M, male.