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. 2020 Sep 15;19:138. doi: 10.1186/s12933-020-01104-6

Table 3.

Association of mean BMI and BMI trajectories (“normal”, “overweight” and “obese”) with indices of carotid stiffness and atherosclerosis estimated by linear regression

Dependent variable β CI p-value
 Distensibility coefficienta
  Mean BMI − 0.275 [− 0.469, − 0.082] 0.005
  Normal weight 0
  Overweight 0.170 [− 1.584, 1.924] 0.849
  Obese − 3.078 [− 5.974, − 0.182] 0.037
 Elastography strain ratio
  Mean BMI 0.006 [− 0.002, 0.015] 0.139
  Normal weight 0
  Overweight − 0.014 [− 0.086, 0.057] 0.698
  Obese 0.181 [0.058, 0.304] 0.004
 Cimt
  Mean BMI 0.005 [0.001, 0.009] 0.026
  Normal weight 0
  Overweight 0.033 [− 0.002, 0.069] 0.068
  Obese 0.095 [0.030, 0.160] 0.004
 Plaque volume groupb
  Mean BMI -0.005 [− 0.053, 0.044] 0.843
  Normal weight CG
  Overweight 0.146 [− 0.286, 0.577] 0.508
  Obese 0.066 [− 0.661, 0.793] 0.858

Models were adjusted to age, gender, diabetes parameters (years of diabetes, medication and HbA1c), blood lipids, CRP, blood pressure, eGFR and smoking status

aDistensibility was not adjusted to blood pressure; bPlaque volume association was estimated by ordinal regression for carotid plaque volume group