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Time to post-baseline EDSS milestones of ⩾4 (a) and ⩾6 (b) confirmed for 12 weeks up to Year 7 categorized by BVL groupa (Baseline to Year 2).
aAnalyses based on pooled data from placebo and active treatment groups (total population); Group 1 (least BVL): ⩽0.52% reduction; Group 2 (intermediate BVL): >0.52% to 2.18% reduction; Group 3 (most BVL): >2.18% reduction.
BVL: brain volume loss; EDSS: Expanded Disability Status Scale.
