Table 3.
Treatment Group | Dose | Liver Weight (g) |
---|---|---|
Normal | 5%DMSO | 1.16±0.09 |
Paracetamol | 250mg/kg | 1.47±0.07a |
Silymarin | 100mg/kg | 1.17±0.06* |
Crude | 100mg/kg | 1.30±0.03 |
200mg/kg | 1.23±0.04 | |
400mg/kg | 1.18±0.02* | |
Aqueous | 100mg/kg | 1.33±0.06 |
200mg/kg | 1.28±0.05 | |
400mg/kg | 1.19±0.06* | |
Chloroform | 100mg/kg | 1.33±0.10 |
200mg/kg | 1.26±0.08 | |
400mg/kg | 1.21±0.04* |
Notes: N= 6, Results were expressed as Mean ±SEM. aP<0.01Vs Normal; *P<0.05 Vs paracetamol. Data were analyzed by One-Way ANOVA followed by Dunnet multiple comparison test.
Abbreviation: DMSO, dimethyl sulfoxide.