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Percentage of Patients That Presented ≥Grade 3 Toxicity as a Function of Their DPD-Enzyme Deficit Status, as Determined by the Multi-Parametric Method.
| Number of patients (472) | Patients with toxicity grade 3, number (%) | Patients with toxicity grade 4, number (%) | Patients with toxicity grade 5, number (%) | |
|---|---|---|---|---|
| Non-deficient | 208 | 4 (1.9%) | 7 (3.4%) | 1 (0.5%) |
| Partially deficient | 239 | 93 (38.9%) | 113 (47.3%) | 23 (9.6%) |
| Totally deficient | 25 | 0 | 8 (32.0%) | 17 (68.0%) |
