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. 2019 Feb 5;9(3):2400–2406. doi: 10.1021/acscatal.9b00118

Table 2. Scope of Different ω-Ene Alkenylcyclopropanes in the Iridium-Catalyzed Tandem Olefinmigration/Cope Rearrangementa.

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a

Reaction conditions: ω-ene alkenylcyclopropane (0.25–0.5 mmol), [Ir(COD)Cl]2 (1.0 mol %), PCy3 (6.0 mol %), NaBArF4 (2.5 mol %), 1,2-DCE (0.5M), 85 °C.

b

Yield of isolated products after purification by flash chromatography.

c

[Ir(COD)Cl]2 (2.5 mol %), PCy3 (15.0 mol %), NaBArF4 (6.25 mol %).

d

Starting material as 60:40 mixture of syn/anti isomers, yield based on syn-isomer

e

Isolated after DIBAL-H reduction: DIBAL-H (250 mol %), THF (0.1M), −78 °C to room temperature.