Table 3. Product Purities, PurR and PurS, and Masses, mR and mS (Dry Product), as Well as Process Times, tproc, and Productivities, PrR and PrS, of All CPCD Experiments Performeda.
| Exp. | mseed [g] | msol.feed [g] | mR [g] | PurR [%] | mS [g] | PurS [%] | tproc [h] | PrR [g/(kg h)] | PrS [g/(kg h)] |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 0.1 | (37) | 0.8 | 99 | 4.3 | 0.36 | |||
| 2 | 0.1 | 20 | 1.4 | 98 | 6.3 | 0.45 | |||
| 3 | 0.1 | 4 | 2.4 | 97 | 0.6 | 91 | 7.2 | 0.68 | 0.17 |
| 4 | 0.1 | 3.5 | 1.8 | 98 | 1.2 | 95 | 6.7 | 0.55 | 0.37 |
| 5 | 0.3 | 10 | 4.3 | 98 | 3.5 | 97 | 5.8 | 1.49 | 1.26 |
| 6 | 1.1 | 20 | 19.6 | 80 | 11.2 | 98 | 3.5 | 9.31 | 6.63 |
| 7 | 1.1 | 30 | 13.8 | 97 | 8.8 | 98 | 1.9 | 14.27 | 9.39 |
| 8 | 1.1 | 30 | 31.6 | 69 | 8.9 | 98 | 3.3 | 14.03 | 5.47 |
| 9 | 1.1 | 30 | 11.3 | 98 | 14.5 | 98 | 2.7 | 9.05 | 10.89 |
| 10 | 1.1 | 30 | 16.1 | 93 | 14.9 | 98 | 4.0 | 7.67 | 7.55 |
| 11 | 1.1 | 40 | 32.7 | 97 | 16.9 | 98 | 4.0 | 16.86 | 9.13 |
Seeding was always done with (R)-guaifenesin except for Exp. 9, where the (S)-enantiomer was used.