Table 3.

Association of Potential Adjustment Factors with Progression Free Survival

		Unadjusted
Variable	Level	HR (95% CI)	P
Age		0.99 (0.96, 1.03)	0.6628
Sex	Female (Reference = Male)	1.24 (0.63, 2.46)	0.5350
ECOG	0 (Reference = 1 or 2)	1.22 (0.63, 2.37)	0.5554
Smoking Status	Current Smoker (Reference = Quit Smoking)	0.98 (0.48, 2.00)	0.2816
	Never Smoker (Reference = Quit Smoking)	0.37 (0.10, 1.37)
Disease Stage	IIIA (Reference = IV)	1.07 (0.25, 4.54)	0.7842
	IIIB (Reference = IV)	1.38 (0.56, 3.37)

Individual unadjusted Cox proportional hazards models were used for each potential adjustment factor

Global p-values presented for categorical variables with more than 2 levels