Table 2.
Characterization of Healthy and MetS Mice.
| Healthy Control | Healthy AgNPs | MetS Control | MetS AgNPs | |
|---|---|---|---|---|
| Body Weight (g) | 34.3 ± 0.9 | 32.6 ± 1.7 | 50.4 ± 1.1# | 48.75 ± 1.2# |
| HDL (mg/dL) | 132.7 ± 10.1 | 128.7 ± 13.4 | 220.9 ± 10.7# | 244.3 ± 19.18# |
| LDL/VLDL (mg/dL) | 43.1 ± 1.3 | 46.3 ± 2.7 | 56.1 ± 2.7# | 61.3 ± 4.1# |
| Total Cholesterol (mg/dL) | 159.8 ± 12.9 | 157.8 ± 10.3 | 273.5 ± 18.6# | 298.4 ± 16.1# |
| Insulin (ng/mL) | 0.53 ± 0.1 | 0.59 ± 0.1 | 8.26 ± 2.4# | 7.52 ± 2.1# |
| % HBA1c | 4.21 ± 0.1 | 4.45 ± 0.2 | 4.55 ± 0.6 | 4.78 ± 0.2 |
Serum from healthy and MetS mice was characterized for traditional lipid endpoints via commercially available kits to measure total bound and unbound cholesterol, HDL, LDL/VLDL, insulin, and glycated hemoglobin (HBA1c).
denotes statistical significance as compared to the corresponding healthy group. Comparisons were performed by two-way ANOVA with Tukey post hoc analysis; p<0.05). All analyses are reported as mean ± SEM, n= 7–8/group.