Table 3.
Mean differences of antigen expression prior and 48-72 hours following subcutaneous denosumab administration. CD14/C23/CD123/CD16 stainings. Thirty postmenopausal osteoporotic women under treatment with denosumab.
| Staining | Paired Differences | ||||
|---|---|---|---|---|---|
| Mean | Std. Deviation | 95% Confidence Interval of the Difference | p-value | ||
| Lower | Upper | ||||
| CD14+/CD23+ | 7,193 | 17,25673 | 0,223 | 14,163 | 0,044 |
| CD14+/CD23- | 13,358 | 37,36448 | -1,733 | 28,450 | ,080 |
| CD14-/CD23+ | ,605 | 1,45269 | ,018 | 1,191 | ,044 |
| CD14-/CD23- | -1,511 | 26,79658 | -9,312 | 12,334 | ,776 |
| CD14+/CD123+ | 8,461 | 16,00697 | 2,128 | 14,793 | ,011 |
| CD14+/CD123- | 10,161 | 19,03547 | 2,631 | 17,691 | ,010 |
| CD14-/CD123+ | -2,273 | 5,28709 | -4,364 | -,181 | ,034 |
| CD14-/CD123- | -,699 | 15,71201 | -6,914 | 5,516 | ,819 |
| CD14+/CD16+ | -7,502 | 17,76660 | -14,531 | -,474 | ,037 |
| CD14+/CD16- | -8,773 | 17,32542 | -15,627 | -1,919 | ,014 |
| CD14-/CD16+ - CD14-/CD16+ | 5,394 | 12,06589 | ,620 | 10,167 | ,028 |
| CD14-/CD16- - CD14-/CD16- | -2,902 | 10,83524 | -7,188 | 1,384 | ,176 |
Statistical significance typed in bold. Increase (positive difference) typed in green. Decrease (negative difference) typed in red.