TABLE 1.
Baseline patient characteristics by worsening organ failure at 48 hours
| Variable | Category | Overall (n = 428) | Worsening organ failure (n = 152) | No worsening organ failure (n = 276) | P‐value |
|---|---|---|---|---|---|
| Age^ | 65 (14) | 67 (14) | 63 (14) | 0.007 a | |
| Sex | Female | 217 (51) | 79 (52) | 138 (50) | 0.696 b |
| Race | Black | 222 (52) | 81 (53) | 141 (51) | 0.162 b |
| White | 179 (42) | 66 (43) | 113 (41) | ||
| Other | 27 (6) | 5 (2) | 22 (8) | ||
| Comorbidities | |||||
| AIDS | Yes | 8 (2) | 3 (2) | 5 (2) | 1.000 c |
| Cancer | Yes | 46 (11) | 19 (13) | 27 (10) | 0.392 b |
| CHF | Yes | 121 (28) | 37 (24) | 84 (31) | 0.173 b |
| COPD | Yes | 164 (38) | 58 (38) | 106 (39) | 0.937 a |
| CVD | Yes | 44 (10) | 9 (6) | 35 (13) | 0.027 b |
| Diabetes mellitus | Yes | 174 (41) | 54 (36) | 120 (43) | 0.109 a |
| Dementia | Yes | 32 (7) | 6 (4) | 26 (9) | 0.039 b |
| ESRD | Yes | 51 (12) | 23 (15) | 28 (10) | 0.128 b |
| Liver disease | Yes | 73 (17) | 34 (22) | 39 (14) | 0.030 a |
| Myocardial infarction | Yes | 50 (12) | 22 (14) | 28 (10) | 0.187 b |
| Metastatic cancer | Yes | 13 (3) | 7 (5) | 6 (2) | 0.999 c |
| Charlson comorbidity indexΨ | 3 (1;4) | 3 (1;4) | 3 (1;4) | 0.842 b |
Data are counts (percentages), unless otherwise specified ^mean (SD), Ψfor median (first quartile; third quartile). AIDS, acquired immune deficiency syndrome; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVD, cerebrovascular disease; ESRD, end stage renal disease.
a
Student t test.
b
Pearson's χ2 test.
c
Fisher's exact test.