Table 2. University Hospital of Zurich Guideline-Preoperative treatment of anemia.

Hemoglobin	Iron parameters	Treatment
	Kidney function
	(Low grade) infection
Hemoglobin <130 g/L “ID Anemia”*	Ferritin <100 µg/L or TSAT <20%	20 mg/kg BW iron carboxymaltose (IV) 30 min + 1 mg vitamin B12 (sc) + 5 mg folic acid (po)
	CCL ≥50 mL/min
Hemoglobin <130 g/L “Renal anemia”	Ferritin ≥100 µg/L and TSAT ≥20%	Epoetin alpha 600 U/kg BW
	CCL <50 mL/min	20 mg/kg BW iron carboxymaltose (IV) 30 min + 1 mg vitamin B12 (sc) + 5 mg folic acid (po)
Hemoglobin <130 g/L “Anemia of chronic disease”	Ferritin ≥100 µg/L and TSAT ≥20%	Epoetin alpha 600 U/kg BW
	CRP >5 mg/L	20 mg/kg BW iron carboxymaltose (IV) 30 min + 1 mg vitamin B12 (sc) + 5 mg folic acid (po)
Hemoglobin ≥130 g/L “Isolated ID”	Ferritin <100 µg/L or TSAT <20%	20 mg/kg BW iron carboxymaltose (IV) 30 min
*Surgery in <5 days additionally Epoetin alpha 600 U/kg BW; TSAT: Transferrin saturation; CCL: Creatinine clearance; IV: Intravenous; po: Per oral; sc: Subcutaneous; BW: Body weight; CRP: C-reactive protein; ID: Iron deficiency.