TABLE 3.

Linear regression models to explain the variance of memory (MEM).

	IL-1β				IL-1RA				IL-6
	B	SE	β	t	B	SE	β	t	B	SE	β	t
Sexa	0.186	0.208	0.077	0.896	0.298	0.212	0.123	1.403	0.104	0.209	0.043	0.499
Age	–0.036	0.012	–0.253	−3.043**	–0.033	0.012	–0.226	−2.743**	–0.026	0.012	–0.178	−2.084*
School years	0.061	0.031	0.182	1.955*	0.070	0.031	0.209	2.262*	0.070	0.031	0.209	2.274*
GDS	–0.425	0.106	–0.364	−3.995***	–0.463	0.107	–0.390	−4.340***	–0.446	0.105	–0.380	−4.262***
Anti-inflammatory drugs	0.017	0.281	0.005	0.061	0.102	0.280	0.030	0.363	–0.009	0.283	–0.003	–0.031
IL-1β	–0.098	0.046	–0.175	−2.131*
IL-1RA					–0.003	0.001	–0.186	−2.253*
IL-6 (log10)									–1.470	0.702	–0.175	−2.096*
F(df1. df2)	8.595(6;106)***				8.821(6;107)***				8.914(6;108)***
R2 (change)	0.327(0.029)				0.331(0.032)				0.331(0.027)
Adjusted R2	0.289				0.293				0.294
	IL-13				IP-10				TNF
	B	SE	β	t	B	SE	β	t	B	SE	β	t
Sexa	0.184	0.202	0.076	0.911	0.173	0.208	0.071	0.831	0.167	0.207	0.068	0.807
Age	–0.033	0.012	–0.228	−2.793**	–0.023	0.013	–0.157	–1.792	–0.030	0.012	–0.206	−2.493*
School years	0.072	0.031	0.214	2.332*	0.067	0.031	0.200	2.158*	0.062	0.031	0.186	2.008*
GDS	–0.402	0.104	–0.343	−3.865***	–0.453	0.105	–0.387	−4.320***	–0.450	0.105	–0.381	−4.291***
Anti-inflammatory drugs	–0.040	0.277	–0.012	–0.144	–0.047	0.279	–0.014	–0.170	0.033	0.276	0.010	0.118
IL-13	–0.074	0.024	–0.244	−3.026**
IP-10					–0.002	0.001	–0.180	−2.112*
TNF									–0.038	0.017	–0.175	−2.174*
F(df1. df2)	9.745(6;105)***				8.575(6;107)***				9.079(6;107)***
R2 (change)	0.358(0.056)				0.325(0,028)				0.337(0.029)
Adjusted R2	0.321				0.287				0.300

SE, standard error; GDS, Geriatric Depression Scale. ^aReference category is male. *p ≤ 0.05, **p < 0.01, ***p < 0.001.