TABLE 3.

Clinicopathological characteristics of the 6-marker-based classifier with OS in the training set and validating set.

Features	Training set (n = 265)			Validating set (n = 133)
	Low risk (n = 133)	High risk (n = 132)	P	Low risk (n = 67)	High risk (n = 66)	P
Age (years), n (%)
≤70	78 (29.4)	60 (22.6)		42 (31.6)	30 (22.6)
>70	55 (20.8)	72 (27.2)	0.032	25 (18.8)	36 (27.1)	0.046
Gender, n (%)
Male	101 (38.1)	88 (33.2)		52 (39.1)	48 (36.1)
Female	32 (12.1)	44 (16.6)	0.095	15 (11.3)	18 (13.5)	0.514
Pathological stage, n (%)
I + II	58 (21.9)	27 (10.2)		29 (21.8)	12 (9.0)
III + IV	75 (28.3)	105 (39.6)	<0.001	38 (28.6)	54 (40.6)	0.002
Histologic grade, n (%)
Low	11 (4.2)	2 (0.8)		7 (5.3)	0 (0)
High	122 (46.0)	130 (49.1)	0.011	60 (45.1)	66 (49.6)	0.007
Diagnosis subtype, n (%)
Non-papillary	76 (28.7)	99 (37.4)		45 (33.8)	51 (38.3)
Papillary	57 (21.5)	33 (12.5)	0.002	22 (16.5)	15 (11.3)	0.193

OS, Overall survival. Bold values are significant to p < 0.05.