TABLE 2.
Clinicodemographic characteristics of the 93 colorectal cancer patients by proband.
| Characteristic | LS group (N = 47) | FCCTX group (N = 46) | χ2/t-value | p-Value |
| Gender | 1.428 | 0.232 | ||
| Male | 26(55.3%) | 31(67.4%) | ||
| Female | 21(44.7%) | 15(32.6%) | ||
| Age (years)a | 44.36 ± 11.26 | 53.57 ± 12.88 | −9.204 | <0.001 |
| <50 | 35(74.5%) | 23(50.0%) | 5.930 | 0.015 |
| ≥50 | 12(2.5.5%) | 23(50.0%) | ||
| CEA (ng/ml) | 2.461 | 0.117 | ||
| <5.2 | 7(14.9%) | 13(28.3%) | ||
| ≥5.2 | 40(85.1%) | 33(71.7%) | ||
| CA19-9 (u/ml) | ||||
| <40 | 11(23.4%) | 7(15.2%) | 0.998 | 0.318 |
| ≥40 | 36(76.6%) | 39(84.8%) | ||
| Primary CRC location | 12.823 | 0.005 | ||
| Right colon | 18(38.3%) | 11(23.9%) | ||
| Left colon | 20(42.6%) | 12(26.1%) | ||
| Rectum | 5(10.6%) | 20(43.5%) | ||
| Multiple | 4(8.5%) | 3(6.5%) | ||
| Multiple tumors | 1.521 | 0.217 | ||
| Occurrence | 12(25.5%) | 7(15.2%) | ||
| Absence | 35(74.5%) | 39(84.8%) | ||
| Tumor sizea (cm) | 5.17 ± 2.61 | 4.35 ± 2.02 | 1.703 | 0.092 |
| Pathological classification | 8.943 | 0.011 | ||
| Adenocarcinoma | 34(72.3%) | 42(91.3%) | ||
| Adenocarcinoma with partial mucinous adenocarcinoma | 5(10.7%) | 4(8.7%) | ||
| Mucinous adenocarcinoma | 8(17.0%) | 0(0.0%) | ||
| Differentiation | 7.839 | 0.020 | ||
| Well differentiated | 1(2.1%) | 2(4.4%) | ||
| Moderately differentiated | 28(59.6%) | 38(82.6%) | ||
| Poorly differentiated | 18(38.3%) | 6(13.0%) | ||
| Cancerous node | 3.196 | 0.074 | ||
| Occurrence | 2(4.3%) | 7(15.2%) | ||
| Absence | 45(95.7%) | 39(84.8%) | ||
| Vascular invasion | 0.056 | 0.813 | ||
| Occurrence | 8(17.0%) | 7(15.2%) | ||
| Absence | 39(83.0%) | 39(84.8%) | ||
| Perineural invasion | 0.002 | 0.968 | ||
| Occurrence | 6(12.8%) | 6(13.0%) | ||
| Absence | 41(87.2%) | 40(87.0%) | ||
| T stage | 0.932 | 0.628 | ||
| T1 | 7(14.9%) | 9(19.6%) | ||
| T2 | 8(17.0%) | 5(10.9%) | ||
| T3 | 32(68.1%) | 32(69.5%) | ||
| N stage | ||||
| N0 | 34(72.3%) | 32(69.6%) | 1.118 | 0.572 |
| N1 | 9(19.1%) | 7(15.2%) | ||
| N2 | 4(8.6%) | 7(15.2%) | ||
| Metastasis | 0.323 | 0.570 | ||
| Occurrence | 2(4.3%) | 1(2.2%) | ||
| Absence | 45(95.7%) | 45(97.8%) | ||
| TNM stage | 0.492 | 0.921 | ||
| I | 13(27.7%) | 10(21.7%) | ||
| II | 17(36.2%) | 20(43.5%) | ||
| III | 15(31.8%) | 15(32.6%) | ||
| IV | 2(4.3%) | 1(2.2%) |
aThese data are presented as mean ± standard deviation; other values are presented as number of patients followed by percentage in parentheses. CRC, colorectal cancer; LS, Lynch syndrome; FCCTX, familial colorectal cancer type X.