TABLE 3.
Tumor characteristics by proband in the 93 patients with colorectal cancer.
| Characteristic | LS group (N = 47) | FCCTX group (N = 46) | χ2/t-value | p-Value |
| Earliest onset age of CRC (years)a | 44.36 ± 11.26 | 53.57 ± 12.88 | −3.671 | <0.001 |
| Total number of CRCsa | 1.55 ± 0.75 | 1.22 ± 0.47 | 2.607 | 0.011 |
| Metachronous CRC | 16(34.0%) | 6(13.0%) | 5.676 | 0.017 |
| Synchronous or metachronous CRC | 20(42.6%) | 9(19.6%) | 4.609 | 0.032 |
| Distant metastasis | 9(19.1%) | 14(30.4%) | 1.591 | 0.207 |
| Right colon cancer | 28(59.6%) | 16(34.8%) | 5.732 | 0.017 |
| Left colon cancer | 30(63.8%) | 16(34.8%) | 7.784 | 0.005 |
| Rectal cancer | 8(17.0%) | 24(52.2%) | 11.219 | 0.001 |
| Earliest onset age of extra-colorectal cancer (years)a* | 48.45 ± 12.68 | 53.38 ± 7.87 | −0.967 | 0.347 |
| Synchronous or metachronous extra-colorectal cancer | 11(23.4%) | 7(15.2%) | 1.203 | 0.252 |
| Earliest onset age of cancer (years)* | 43.40 ± 11.17 | 52.87 ± 12.31 | −3.885 | <0.001 |
aThese data are presented as mean ± standard deviation; other values are presented as number of patients followed by percentage in parentheses. ∗These data are limited to patients who developed extra-colorectal cancer. LS, Lynch syndrome; CRC, colorectal cancer; FCCTX, familial colorectal cancer type X.