Table 3.
Genotyping of the ERCC-1 gene single nucleotide polymorphisms.
Genotype | N (%) |
---|---|
T19007C | |
TT (reference genotype) | 24 (53) |
CT (heterozygous variant) | 19 (42) |
CC (homozygous variant) | 2 (5) |
CT + CC (polymorphic genotype) | 21 (47) |
C8092A | |
CC (reference genotype) | 29 (64) |
AC (heterozygous variant) | 12 (27) |
AA (homozygous variant) | 4 (9) |
AC + AA (polymorphic genotype) | 16 (36) |
Both T19007C + C8092A PG* | 11 (24) |
Only T19007C PG | 10 (22) |
Only C8092A PG | 5 (11) |
No T19007C PG nor C8092A PG | 19 (42) |
Odds Ratio = 4.18 (95% CI, 1.13–15.42); P = 0.027.