TABLE 2.
Cytokines, T lymphocyte subsets, and classification of leukocytes in patients with COVID-19 (N = 230).
| Variable | First test | Last test | Statistical test |
| IL-2 (pg/ml) | 2.52 (0.68) (n = 216) | 3.68 (1.17) (n = 84) | Z = −7.044, P < 0.001 (n = 81) |
| IL-4 (pg/ml) | 2.03 (1.16) (n = 215) | 3.56 (1.47) (n = 84) | Z = −6.901, P < 0.001 (n = 81) |
| IL-6 (pg/ml) | 16.70 (61.88) (n = 216) | 9.82 (35.96) (n = 84) | Z = −2.744, P = 0.006 (n = 81) |
| IL-10 (pg/ml) | 3.00 (1.87) (n = 216) | 4.79 (2.20) (n = 82) | Z = −5.904, P < 0.001 (n = 79) |
| TNF-α (pg/ml) | 3.10 (2.52) (n = 216) | 4.40 (4.43) (n = 84) | Z = −5.172, P < 0.001 (n = 81) |
| INF-γ (pg/ml) | 1.96 (1.25) (n = 216) | 3.45 (1.30) (n = 81) | Z = −5.811, P < 0.001 (n = 78) |
| CD3+ (%) | 76.22 (12.62) (n = 217) | 76.55 ± 10.09 (n = 35) | Z = −0.068, P = 0.946 (n = 31) |
| CD4+ (%) | 46.29 ± 10.61 (n = 218) | 46.10 ± 12.53 (n = 35) | t = 1.404, P = 0.171 (n = 31) |
| CD8+ (%) | 24.56 ± 9.56 (n = 218) | 23.65 ± 7.97 (n = 35) | t = 0.711, P = 0.483 (n = 31) |
| CD4+/CD8+ | 2.02 (1.26) (n = 218) | 2.27 ± 1.08 (n = 35) | Z = −0.843, P = 0.399 (n = 31) |
| WBC (109/l) | 5.36 (2.31) (n = 230) | 5.65 ± 1.52 (n = 79) | Z = −0.237, P = 0.813 (n = 79) |
| N (109/l) | 3.23 (1.81) (n = 230) | 3.01 (1.66) (n = 78) | Z = −1.594, P = 0.111 (n = 78) |
| L (109/l) | 1.38 ± 0.50 (n = 230) | 1.58 (0.63) (n = 78) | Z = −3.131, P = 0.002 (n = 78) |
| M (109/l) | 0.51 (0.30) (n = 148) | 0.49 (0.21) (n = 78) | Z = −1.432, P = 0.152 (n = 78) |
| N/LRs | 2.44 (1.52) (n = 230) | 1.92 (1.09) (n = 78) | Z = −3.813, P < 0.001 (n = 78) |
| IL-6/lL-10 | 5.32 (17.59) (n = 216) | 2.01 (8.64) (n = 82) | Z = −4.272, P < 0.001 (n = 79) |