Table 4.
CT-DNA-binding data from UV-Vis absorption and fluorescence emission of boron complexes.
| CT-DNA by absorption | EB-DNA by emission | ||||||
|---|---|---|---|---|---|---|---|
| Comp. | H(%)a | Δλ(nm)b | Kb(M-1)c | ΔG°(kcal/mol)d | Q(%)e | KSV(M-1)f | kq(M-1 s-1)g |
| 6a | 3.55 | 0.0 | 1.67 × 105 | −7.12 | 7.08 | 7.47 × 102 | 3.24 × 1010 |
| 6b | 3.68 | 0.0 | 1.72 × 105 | − 7.13 | 3.45 | 3.44 × 102 | 1.49 × 1010 |
| 6c | 6.26 | 3.0 | 2.44 × 105 | − 7.34 | 10.95 | 1.17 × 103 | 5.09 × 1010 |
| 6d | 4.07 | 0.0 | 1.85 × 105 | − 7.17 | 4.85 | 5.07 × 102 | 2.20 × 1010 |
| 6e | 4.74 | 0.0 | 1.98 × 105 | − 7.22 | 5.86 | 6.72 × 102 | 2.92 × 1010 |
| 6f | 3.10 | 6.0 | 1.51 × 105 | − 7.06 | 5.43 | 3.26 × 102 | 1.42 × 1010 |
| 6g | 2.11 | 6.0 | 1.17 × 105 | − 6.90 | 14.53 | 1.64 × 103 | 7.13 × 1010 |
| 6h | 4.85 | 0.0 | 2.23 × 105 | − 7.28 | 7.02 | 6.98 × 102 | 3.03 × 1010 |
| 6i | 3.68 | 0.0 | 1.76 × 105 | − 7.14 | 11.34 | 1.20 × 103 | 5.22 × 1010 |
| 7e | 7.06 | 0.0 | 4.76 × 105 | − 7.73 | 7.31 | 9.05 × 102 | 3.93 × 1010 |
a
H(%) = (Absinitial − Absfinal)/(Absinitial) × 100 at 300–400 nm range;
b
Δλ (nm) = λ final- λ initial;
c
Binding constant by UV-Vis CT-DNA analysis;
d
Gas constant R = 1.9858775 kcal K-1 mol-1 and temperature T = 298K;
e
Q(%) = (Emissioninitial − Emissionfinal)/(Emissioninitial) × 100;
f
Stern-Volmer quenching EB-DNA constant (KSV) by steady-state emission spectra;
g
Stern-Volmer rate quenching EB-DNA constant (kq) by steady-state emission spectra.