Table 3.
Adjusted ORs for BASC-2 and CBCL scores in the borderline or clinical range for each 1-unit increase in unadjusted prenatal phthalate concentration quartiles for low molecular weight phthalates (i.e., MBP, MiBP, MEP, MMP, ΣLMWP).
| MBPa OR (95% CI) |
MiBPa OR (95% CI) |
MEPa OR (95% CI) |
MMPa OR (95% CI) |
ΣLMWPb OR (95% CI) |
|
|---|---|---|---|---|---|
| BASC-2 | |||||
| Externalizing Problems | 1.33 (0.82, 2.15) | 1.39 (0.83, 2.32) | 1.34 (0.89, 2.02) | 1.09 (0.71, 1.68) | 1.36 (0.89, 2.08) |
| Internalizing Problems | 1.46 (0.99, 2.14) | 1.93*** (1.25, 3.00) | 1.13 (0.81, 1.57) | 1.12 (0.80, 1.57) | 1.32 (0.92, 1.87) |
| BSI | 1.45 (0.94, 2.24) | 1.59 (0.99, 2.55) | 1.09 (0.76, 1.58) | 1.23 (0.83, 1.83) | 1.14 (0.78, 1.67) |
| Hyperactivity | 1.33 (0.89, 1.98) | 1.18 (0.77, 1.82) | 1.13 (0.81, 1.58) | 0.99 (0.69, 1.42) | 1.16 (0.82, 1.65) |
| Aggression | 1.21 (0.77, 1.90) | 1.78** (1.10, 2.88) | 1.02 (0.71, 1.47) | 1.16 (0.78, 1.72) | 1.12 (0.76, 1.65) |
| Anxiety | 1.37* (1.00, 1.88) | 1.47* (1.03, 2.11) | 0.96 (0.73, 1.26) | 1.17 (0.88, 1.56) | 1.10 (0.82, 1.46) |
| Depression | 1.04 (0.70, 1.56) | 1.78** (1.14, 2.79) | 1.11 (0.79, 1.56) | 0.96 (0.68, 1.36) | 1.31 (0.91, 1.88) |
| Somatization | 1.43 (0.85, 2.41) | 1.73 (0.95, 3.14) | 1.04 (0.67, 1.64) | 0.95 (0.60, 1.50) | 1.09 (0.67, 1.78) |
| Atypicality | 1.11 (0.80, 1.54) | 1.25 (0.87, 1.80) | 0.98 (0.75, 1.30) | 1.09 (0.82, 1.46) | 0.94 (0.70, 1.27) |
| Withdrawal | 1.14 (0.76, 1.71) | 1.28 (0.82, 2.00) | 1.19 (0.85, 1.68) | 1.03 (0.73, 1.47) | 1.09 (0.76, 1.58) |
| Attention Problems | 1.30 (0.88, 1.93) | 1.27 (0.83, 1.94) | 1.10 (0.79, 1.53) | 0.97 (0.68, 1.37) | 1.12 (0.79, 1.58) |
| CBCL | |||||
| Externalizing Problems | 1.45 (0.95, 2.21) | 1.47 (0.93, 2.32) | 1.33 (0.93, 1.91) | 1.18 (0.81, 1.72) | 1.34 (0.92, 1.95) |
| Internalizing Problems | 1.49 (0.99, 2.25) | 1.12 (0.71, 1.75) | 1.03 (0.73, 1.45) | 1.09 (0.76, 1.56) | 1.02 (0.71, 1.48) |
| Total Problems | 1.25 (0.80, 1.93) | 1.30 (0.80, 2.11) | 1.02 (0.71, 1.48) | 1.29 (0.87, 1.91) | 0.99 (0.67, 1.47) |
| ADH Problems | 1.78 (0.36, 8.78) | 0.91 (0.15, 5.66) | 0.55 (0.11, 2.67) | 0.98 (0.21, 4.56) | 0.46 (0.08, 2.74) |
| Aggressive Behaviour | 1.12 (0.53, 2.39) | 1.84 (0.83, 4.07) | 1.45 (0.77, 2.73) | 1.31 (0.66, 2.63) | 1.41 (0.75, 2.68) |
| Anxious/Depressed | 1.55 (0.64, 3.78) | 1.64 (0.63, 4.27) | 2.56* (1.00, 6.57) | 1.14 (0.50, 2.59) | 2.48 (0.97, 6.34) |
| Anxiety Problems | 1.42 (0.78, 2.57) | 1.06 (0.55, 2.05) | 1.61 (0.94, 2.74) | 1.19 (0.69, 2.08) | 1.59 (0.93, 2.72) |
| Affective Problems | 1.05 (0.66, 1.66) | 1.08 (0.65, 1.81) | 0.91 (0.61, 1.34) | 1.18 (0.79, 1.78) | 0.92 (0.60, 1.40) |
| Somatic Complaints | 1.11 (0.64, 1.93) | 0.73 (0.39, 1.34) | 1.19 (0.75, 1.88) | 1.02 (0.64, 1.63) | 1.08 (0.66, 1.77) |
| PD Problems | 1.32 (0.79, 2.24) | 1.24 (0.71, 2.16) | 1.53 (0.97, 2.40) | 1.14 (0.72, 1.81) | 1.46 (0.92, 2.32) |
| Withdrawn | 1.17 (0.59, 2.34) | 1.08 (0.52, 2.25) | 1.25 (0.70, 2.24) | 1.34 (0.71, 2.52) | 1.05 (0.58, 1.93) |
| Attention Problems | 1.58 (0.90, 2.79) | 1.71 (0.89, 3.27) | 1.57 (0.94, 2.62) | 0.85 (0.50, 1.47) | 1.46 (0.87, 2.47) |
All models are adjusted for urinary creatinine, family income, child sex, and Full-Scale Intelligence Quotient (FSIQ).
a
μg/L.
b
μmol/L.
*
Raw p-value < 0.05.
**
q < 0.10.
***
q < 0.05.