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. Author manuscript; available in PMC: 2021 Oct 14.
Published in final edited form as: Neuroreport. 2020 Oct 14;31(15):1084–1089. doi: 10.1097/WNR.0000000000001520

Fig. 1. Schematic of the experimental protocol.

Fig. 1.

(A) Rats underwent a right C7 nerve root compression immediately followed by intrathecal treatment with an sPLA2 inhibitor, no treatment, or a sham surgery. Behavioral testing was performed on the ipsilateral forepaw on days 0 and 1 and electrophysiology recording of the ipsilateral C6 or C7 spinal cord during mechanical stimulation of the ipsilateral forepaw was performed on day 1. C6 spinal cord tissue was used for either RT-qPCR or sPLA2 activity analysis. (B) Genes for glutamate receptors and transporters, substance P (SP) and pro-inflammatory cytokines were assayed using published primer sequences [2;15–18].