Table 5.
Time of analysis and solvent consumption using different procedures of sample preparation applied in the research.
| Standard/reference procedure | SFPE-vials-LCMS | SFPE-vials-MS | SFPE-MS | |
|---|---|---|---|---|
| Sample preparation step | ||||
| Time per sample (min) | 2.5 | 3.0 | 3.0 | 2.3 |
| Automation | No | Partial | ||
| Quantitative analysis | ||||
| Time per sample (min) |
13.5 (flushing and injection + analysis + column flushing by gradient + column equalibration) |
13.5 (*4.5) (flushing and injection + analysis + column flushing by gradient + column equalibration) |
2.0 (flushing and injection + analysis) |
2.0 (analysis + flushing) |
| Total analysis time (min) | 16.0 | 16.5 (*7.5) | 5.0 | 4.3 |
| Average consumption of solvents (mL) | 150 | 150 (70) | 60 | 35 |