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. Author manuscript; available in PMC: 2020 Sep 16.
Published in final edited form as: Cell Rep. 2020 Sep 8;32(10):108052. doi: 10.1016/j.celrep.2020.108052

Figure 3. Deletion of Tnfrsf11b from Osteocytes Results in a Mild Decrease in Bone Mass.

Figure 3.

(A) Cortical thickness in the femur and L4 vertebra measured by μCT (n = 6–7).

(B) Cancellous BV/TV of femurs and L4 vertebra (n = 6–7).

(C) Cross sections of the femoral diaphysis viewed by μCT. Scale bar, 500 μm.

(D) μCT images of vertebral cancellous bone. Scale bar, 500 μm.

(E) Quantitative analysis of cortical porosity of femurs measured by μCT (n = 5–7).

(F) Tnfrsf11b, Tnfsf11, TRAP, and CTSK mRNA levels in tibial cortical bone (n = 6–8). All values are from 5-week-old female mice of the indicated genotypes, and bars are means ± SD. Cortical thickness, BV/TV, and cortical porosity values for Tnfrsf11b+/+ and Tnfrsf11b−/− mice are the same as in Figures 1 and 2. The indicated p values were determined by one-way ANOVA.

See also Figures S1 and S3 and Data S1.