Table 1.

IMWG frailty score^*.

Variable	Hazard ratio (CI 95%)	p value	Score
Age
<75 years	1	–	0
75–80 years	1.37 (0.93–2.03)	0.114	1
>80 years	2.75 (1.81–4.18)	<0.001	2
Charlson index	1	–	0
≤1
≥2	1.6 (1.07–2.39)	0.021	1
ADL score	1	–	0
>4
≤4	1.76 (1.14–2.71)	0.01	1
IADL score	1	–	0
>5
≤5	1.53 (1.03–2.27)	0.036	1
Additive total score	Patient status
0	Fit
1	Unfit
≥2	Frail

IMWG: The International Myeloma Working Group; ADL: activities of daily living; IADL: instrumental activities of daily living.

^*Adapted from Palumbo et al. [5].