Figure 1.
Effect of age on aging marker abnormality. Aging markers were defined as abnormal based on the value of the worst 5th percentile in the youngest age group (60–70 years old) (25) or an amyloid BPND equal to or above a previously defined cut point (26). The cut point value was included in the abnormal group. BPND = nondisplaceable binding potential; CERAD = Consortium for the Establishment of a Registry for Alzheimer’s Disease; MMSE = mini-mental state examination; WMH = white matter hyperintensities.