Table 5.

Cost estimates

Measures	Cost estimates	Calculation
Endoscopy	95.13 USD
Biopsy/histology	42.58 USD
RUT	10.88 USD
Quadruple therapy for 10 d	34.67 USD
Standard triple therapy for 10 d	48.4 USD
Genetic testing (DPO-PCR)	47.57 USD
Tailored therapy	250.86 USD	${\text{Cost}}_{\text{endoscopy}}+{\text{Cost}}_{\text{histology}}\mathrm{+}{\text{Cost}}_{\text{RUT}}\mathrm{+}{\text{Cost}}_{\text{DPO\_PCR}\text{test}}\mathrm{+}{\text{Cost}}_{\text{medication}}\mathrm{+}{\text{Cost}}_{{}^{13}\text{C}\mathrm{\_}\text{UBT}}$
Standard therapy	217.86 USD	${\text{Cost}}_{\text{endoscopy}}\mathrm{+}{\text{Cost}}_{\text{histology}}\mathrm{+}{\text{Cost}}_{\text{RUT}}\mathrm{+}{\text{Cost}}_{\text{medication}}\mathrm{+}{\text{Cost}}_{{}^{13}\text{C}\mathrm{\_}\text{UBT}}$
ICERs	2.17 USD per 1% eradication rate gained	$\frac{{\text{Cost}}_{\text{tailored}\text{group}}\mathrm{-}{\text{Cost}}_{\text{empirical}\text{group}}}{\text{Eradication}{\text{rate}}_{\text{tailored}\text{group}}\mathrm{-}\text{Eradication}{\text{rate}}_{\text{empirical}\text{group}}}$

The ICER is defined as the difference in average total costs for the tailored group minus the empirical group divided by the average difference in the eradication rate.

C-UBT, C-urea breath test; DPO-PCR, dual-priming oligonucleotide-based multiplex-polymerase chain reaction test; ICER, incremental cost-effectiveness ratio; RUT, rapid urease test; USD, United States dollars.