Table 2.
Adjusted geometrie mean childhood urinary phthalate metabolite concentrations (ng/mL) and percent differences by combined intervention and post-trial household cleanliness category (The HOME Study; Cincinnati, OH). a
| ∑DEHP | MBzP | MCOP | MCNP | MEP | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Intervention / Cleanliness Category | GM | %Difference (95% CI) | p-valueb | GM | %Difference (95% CI) | p-valueb | GM | %Difference (95% CI) | p-valueb | GM | %Difference (95% CI) | p-valueb | GM | %Difference (95% CI) | p-valueb |
| Control / Does not appear clean | 93 | Ref | 0.020 | 19 | Ref | 0.14 | 13 | Ref | 0.21 | 5.3 | Ref | 0.021 | 57 | Ref | 0.97 |
| Control / Appears clean | 91 | −1 (−18, 19) | 16 | −17 (−34, 4) | 11 | −13 (−27, 4) | 4.4 | −17 (−29, −3) | 60 | 4 (−18, 31) | |||||
| Intervention / Does not appear clean | 94 | 2 (−17, 25) | 17 | −7 (−28, 19) | 12 | −7 (−24, 12) | 4.8 | −9 (−24, 9) | 59 | 2 (−21, 33) | |||||
| Intervention / Appears clean | 73 | −21 (−35, −4) | 14 | −23 (−39, −2) | 10 | −17 (−31, −1) | 4.2 | −22 (−34, −7) | 56 | −2 (−23, 26) | |||||
Model adjusted for child age (continuous), sex (male vs. female), race/ethnicity (Non-Hispanic white vs. Non-Hispanic Black vs. Hispanic or other race/ethnicity), log10-transformed urinary creatinine concentration (continuous), flooring type (carpet vs. non-carpet), maternal education (Bachelor’s degree or higher vs. Tech/some college vs. High school or less), household income ( <$20,000 vs. $20,000 to <$40,000 vs. $40,000 to $70,000 vs. >$70,000), and season (spring vs. summer vs. fall vs, winter).
p-value for effect of combined intervention/cleanliness categorical variable.
Observations: Control/ Does not appear clean = 137; Control/Appears clean = 189; Intervention/ Does not appear clean = 131; Intervention/Appears clean = 193. Abbreviations: GM = geometrie mean; summary DEHP (∑DEHP) = sum of the molar mass of mono-2-ethyl-5-hydroxyhexyl phthalate (MEHHP), mono-2-ethyl-5-oxohexyl phthalate (MEOHP), and mono-2-ethyl-5-carboxypentyl phthalate (MECPP); monobenzyl phthalate (MBzP); monocarboxyoctyl phthalate (MCOP); monocarboxynonyl phthalate (MCNP); monoethyl phthalate (MEP).