Figure 2.
Acute vapourized THC exposure reduces corticostriatal coherence. A-B) Coherence curves and quantification (mean ± SEM) showing no effects of THC (blue or black) on dSTR-OFC coherence (mean ± SEM) compared to VEH (grey or white). C-D) THC administration reduced dStr-PFC coherence selectively in the high gamma range compared to baseline (vehicle) treatment. E-F) Reduced OFC-PFC theta and gamma coherence was observed following THC treatment (n=4 with bilateral electrodes; *p<0.05, ** p<0.01).