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. 2020 Sep 11;13:9043–9057. doi: 10.2147/OTT.S262084

Table 2.

Correlation Between AAPR and Patient Characteristics in Training Cohort

Pre-AAPR≤0.52 Pre-AAPR>0.52 p-value Post-AAPR≤0.52 Post-AAPR>0.52 p-value
Age 0.99 0.12
 <60 63 (50%) 37 (50%) 47 (44.8%) 53 (55.8%)
 ≥60 63 (50%) 37 (50%) 58 (55.2%) 42 (44.2%)
Sex 0.27 0.59
 Male 102 (81%) 55 (74.3%) 84 (80%) 73 (76.8%)
 Female 24 (19%) 19 (25.7%) 21 (20%) 22 (23.2%)
Marital 0.21 0.31
 Married 120 (95.2%) 73 (98.6%) 100 (95.2%) 93 (97.9%)
 Unmarried 6 (4.8%) 1 (1.4%) 5 (4.8%) 2 (2.1%)
BMI 0.73 0.36
 BMI<18.5 6 (4.8%) 3 (4.1%) 5 (4.8%) 4 (4.2%)
 18.5≥BMI<25 76 (60.3%) 41 (55.4%) 66 (62.8%) 51 (53.7%)
 BMI≥25 44 (34.9%) 30 (40.5%) 34 (32.4%) 40 (42.1%)
Smoking History 0.80 0.85
 No 42 (33.3%) 26 (35.1%) 33 (31.4%) 35 (36.8%)
 Yes 84 (66.7%) 48 (64.9%) 72 (68.6%) 60 (63.2%)
Smoking Index 0.85 0.53
 <800 80 (63.5%) 46 (62.2%) 64 (61%) 62 (65.3%)
 ≥800 46 (36.5%) 28 (37.8%) 41 (39%) 33 (34.7%)
KPS 0.085 0.37
 ≥90 66 (52.4%) 48 (66%) 63 (60%) 51 (53.7%)
 <90 60 (47.6%) 26 (34%) 42 (40%) 44 (46.3%)
T Stage 0.17 0.082
 T1-T2 47 (33.3%) 35 (62.7%) 37 (35.2%) 45 (47.4%)
 T3-T4 79 (62.7%) 39 (52.7%) 68 (64.8%) 50 (52.6%)
N Stage 0.15 0.41
 N0-N2 60 (47.6%) 43 (52.4%) 57 (54.3%) 46 (48.4%)
 N3 66 (52.4%) 31 (41.9%) 48 (45.7%) 49 (51.6%)
Brain Metastasis 0.51 0.64
 No 89 (70.6%) 49 (66.2%) 74 (70.5%) 64 (67.4%)
 Yes 37 (29.4%) 25 (33.8%) 31 (29.5%) 31 (32.6%)
Liver Metastasis 0.005 0.17
 No 78 (61.9%) 60 (81.1%) 68 (64.8%) 71 (73.7%)
 Yes 48 (38.1%) 14 (18.9%) 37 (35.2%) 24 (26.3%)
Bone Metastasis 0.06 0.89
 No 81 (64.3%) 57 (77%) 72 (68.6%) 66 (69.5%)
 Yes 45 (35.7%) 17 (23%) 33 (31.4%) 29 (30.5%)
Thoracic Radiotherapy 0.25 0.53
 No 90 (71.4%) 47 (63.5%) 74 (70.5%) 63 (66.3%)
 Yes 36 (28.6%) 27 (36.5%) 31 (29.5%) 32 (33.7%)

Abbreviations: KPS, Karnofsky performance score; BMI, body mass index; AAPR, albumin-to-alkaline phosphatase ratio.