Table 3.

Changes in the stroke epidemiological trends after COVID-19 pandemic: The results of interrupted time series analysis

Variable	Estimate	Standard Error	t	p
Age average (yrs)	0.636	1.48	0.43	0.67
Male/Female ratio	0.085	0.36	0.231	0.818
Hospitalization Rate: Total stroke	-1.03	0.24	-4.19	<0.0001
Hospitalization rate: Ischemic stroke	-1.032	0.21	-4.7	<0.0001
Hospitalization rate: Hemorrhagic stroke	-0.003	0.09	-0.04	0.968
Intravenous thrombolytic therapy*	-0.115	0.05	-1.98	0.042
Stroke Unit admission	0.027	0.077	0.354	0.724
Presentation time (hrs)	-0.355	0.49	-0.712	0.478
Door to Needle time (hrs)	1.057	1.82	0.58	0.563
NIHSS:  <5 at admission*	-2.61	0.53	-4.89	<0.0001
NIHSS: 5–15 at admission*	-0.322	0.15	-2.02	0.047
NIHSS:  16–20 at admission*	-0.216	0.04	-0.526	0.601
NIHSS:  21–42 at admission*	0.041	0.02	1.8	0.069
mRS ≥ 2 at admission	-0.16	0.06	-2.64	0.010
mRS ≥ 2 at discharge	0.581	0.124	4.672	<0.0001
In-hospital mortality**	-0.057	0.07	-0.808	0.421
Length of Stay (day)	-0.47	0.47	-0.993	0.324

Study period: February 18, 2019 to July 18, 2020; First confirmed case: Feb 18, 2020.

Abbreviations: NIHSS: The National Institutes of Health Stroke Scale; mRS: modified Rankin Scale.

* Proportion to ischemic stroke; ** Proportion to total stroke.