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. 2020 Sep 10;12:8303–8312. doi: 10.2147/CMAR.S258487

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© 2020 Li et al.

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SNHG7 silencing inhibited tumor growth in vivo. Xenograft mice were established by subcutaneously injecting A549 and NCI-H1299 cells stably transfected with sh-SNHG7 and sh-NC in mice. Tumor volume was measured every 5 days and tumor weight was measured at 30 days when the mice were sacrificed. (A–B) Tumor volume (A) and weight (B) of A549 xenograft mice. (C–D) Tumor volume (C) and weight (D) of NCI-H1299 xenograft mice. (E) SNHG7 expression in A549 and NCI-H1299 tumor tissues. (F–G) Protein expression of cleaved caspase 3 (F) and PCNA (G) in tumor tissues. *P<0.05.