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. 2020 Sep 10;12:8303–8312. doi: 10.2147/CMAR.S258487

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© 2020 Li et al.

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miR-181a-5p inhibitor abrogated SNHG7 silencing induced inhibition on proliferation, migration and invasion in NSCLC cells. A549 and NCI-H1299 cells were transfected with si-SNHG7, si-SNHG7+anti-miR-181a-5p, si-SNHG7+anti-NC or si-NC. (A) The expression of miR-181a-5p in transfected cells. (B) Cell viability of transfected cells at 24 h, 48 h and 72 h. (C) Cell apoptosis of NSCLC cells at 48 h post transfection. (D) Protein expression of cleaved caspase 3 in transfected cells. (E-F) Cell migration (E) and invasion (F) ability of transfected A549 and NCI-H1299 cells. *P<0.05.