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Effect of Forskolin on CBD-Mediated TRPV1 Desensitization
| Percent Response | Vehicle 0 uMol/L CBD | 20 µMol/L FSK + 1 uMol/L Caps | 1 uMol/L CBD | 20 µMol/L FSK + 1 uMol/L CBD |
|---|---|---|---|---|
| Mean ± sem (n) | 100 ± 6.7 (5) | 95.9 ± 6.1 (5) | 51.3 ± 6.5 (6) | 96 ± 11 (5) |
Note: Data showing the desensitization effects of CBD on capsaicin responses are reversed in the presence of forskolin.
