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Effect of Cyclosporin on CBD-Mediated TRPV1 Desensitization
| Percent Response | Vehicle 0 uMol/L CBD | 100 nMol/L CSP + 1 uMol/L Caps | 1 uMol/L CBD | 100 nMol/L CSP + 1 uMol/L CBD |
|---|---|---|---|---|
| Mean ± sem (n) | 100 ± 6.7 (5) | 90.5 ± 5.6 (5) | 51.3 ± 6.5 (6) | 102.4 ± 14.8 (5) |
Note: Data showing the desensitization of capsaicin responses caused by CBD, is reversed in the presence of cyclosporin.
