Table 3.

CircRNA-Related Signaling Pathways in OSCC

CircRNAs	Expression	Host Gene	Signaling Pathway	Biological Functions in OSCC	Ref
hsa_circ_043621	Up	KRT14	MAPK, PI3K/Akt and Bcl-2/Bax	Promote proliferation; inhibit G0/G1 cell cycle arrest and apoptosis	31
hsa_circ_102459	Down	MAST1	MAPK, PI3K/Akt and Bcl-2/Bax	Suppress proliferation; induce G0/G1 cell cycle arrest and apoptosis	31
hsa_circ_0005379	Down	-	EGFR, Bcl-2/Bax and EMT	Suppress proliferation, migration and invasion	61
hsa_circ_0007059	Down	ZNF720	AKT/mTOR	Suppress proliferation, migration and invasion; induce apoptosis	62
hsa_circ_0055538	Down	RMND5A	p53/Bcl-2/caspase	Suppress proliferation, migration and invasion; induce apoptosis	44

Note: - Means not mentioned in the paper.