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. 2020 Sep 14;6(9):e04819. doi: 10.1016/j.heliyon.2020.e04819

Table 2.

Regression and statistical parameter for the determination of AZI and LEVO using the proposed methods. Sa is standard deviation of intercept, Sb is standard deviation of slope and Sy/x is standard deviation of residuals.

Parameters Method I (Direct)
Method II (D1)
AZI LEVO AZI LEVO
Linearity range (μg/mL) 5.00–50.00 2.50–20.00 5.00–50.00 5.00–40.00
LOQ (μg/mL) 4.69 2.43 4.47 4.56
LOD (μg/mL) 1.55 0.80 1.47 1.50
Intercept (a) 1.72 × 10−2 9.35 × 10−3 5.68 × 10−3 -2.59 × 10−3
Slope (b) 1.71 × 10−2 5.95 × 10−2 5.72 × 10−3 1.67 × 10−2
Correlation coefficient (r) 0.9996 0.9991 0.9995 0.9992
Sa 6.30 × 10−3 1.24 × 10−2 1.99 × 10−3 6.55 × 10−3
Sb 2.07 × 10−4 1.01 × 10−3 6.55 × 10−5 2.66 × 10−4
Sb2 4.28 × 10−8 1.02 × 10−6 4.29 × 10−9 7.08 × 10−8
Sy/x 8.02 × 10−3 1.45 × 10−2 2.56 × 10−3 7.62 × 10−3
F 6828.17 3470.70 7624.17 3951.43
Significance F 3.91 × 10−6 1.08 × 10−5 1.03 × 10−7 8.87 × 10−6