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. 2020 Sep 14;6(9):e04819. doi: 10.1016/j.heliyon.2020.e04819

Table 7.

The penalty points for the determination of AZI and LEVO for the proposed methods and the reported methods.

Reagents/instruments Penalty points
Proposed Methods Reported method [6] Reported method [7]
Methanol 6 - 18
Acetonitrile - 4 -
Chloroform - 2 -
Benzene - 6 -
Ortho-phosphoric acid - - 6
Perchloric acid 4 - -
DDQ - 2 -
Chloranilic acid (p-CA) - 1 -
Crystallization and filtration - 1 -
UV-VIS spectrophotometry 0 0 -
HPLC - - 1
Occupational hazard 0 0 0
Waste >10mL 5 5 5
Total penalty points 15 21 30
Analytical Eco-Scale total score 85 79 70