Table 8.

Collective comparison between the developed and the reported methods for the simultaneous determination of AZI and LEVO mixtures.

Analytical methods		λ(nm)		Linearity range (μg/mL)		Correlation coefficient		LOD		Comments
		AZI	LEVO	AZI	LEVO	AZI	LEVO	AZI	LEVO
Proposed method I		482	224	5.0–50.0	2.5–20.0	0.9996	0.9991	1.55	0.80	∗No need to adjust pH ∗No need of pre-treatment or extraction ∗Non-destructive
Proposed method II		475–490	280–253	5.0–50.0	5.0–40.0	0.9995	0.9992	1.47	1.50
Reported method [4]		536	301	4.0–20.0		0.973	0.9983	1.07	0.84	∗Lengthy ∗Buffer pH adjustment (apt to personal and/or instrumental variations which may affect the ruggedness of the methods) ∗Mandatory filtration of samples and mobile phase ∗Expensive organic solvents
Reported method [6]	Method A	390–650 (AUC)		12.0–225	10.0–200	0.999	0.998	1.4	1.0
	Method B	400–700 (AUC)		40.0–500	30.0–300			5.0	3.0
Reported method [5]	Method I	245	290	20.0–100		0.9971	0.9975	6.0	8.52
	Method II	245	290					4.08	9.50
Reported method [7]		269		50–150		0.99	0.99	34.5	43.6
Reported method [8]		285		50.0–150.0		0.9991	0.999	20.50	18.25
Reported method [9]		285		50.0–150		0.99	0.99	6.13	5.47
Reported method [10]		262		20.0–100	2.0–10.0	0.999	0.999	0.01	0.001