Table 2.
Comparison of laboratory parameters in patients with LCS and CS.
| Variables | LCS (n = 14) | CS (n = 46) | P-value |
|---|---|---|---|
| Age (mean ± SD) (years) | 2.20 ± 0.90 | 2.40 ± 0.54 | 0.309 |
| Weight (kg) (median (IQR)) | 4.50 (2.76–16.18) | 3.50 (2.77–9.10) | 0.342 |
| Gender (Male/Female) | 6/8 | 24/22 | 0.761 |
| WBC (×103/μL) (median (IQR)) | 12.88 (9.66–144.00) | 15.44 (11.30–20.01) | 0.104 |
| Hb (g/dL) (Mean ± SD) | 13.88 ± 3.80 | 11.99 ± 4.29 | 0.147 |
| hs-CRP (μg/L) | 35.29 (22.80–81.10) | 20.70 (12.30–25.52) | 0.001 |
| sCD14 (μg/L) | 69.54 (24.00–132.7) | 22.76 (18.46–28.27) | 0.004 |
| PCT (ng/L) | 1653 (655.1–2033) | 595.1 (459.2–930.3) | 0.001 |
| Platelets (×103/μL) | 125.0 (79.75–144.0) | 165.0 (136.0–211.0) | 0.005 |
| Temperature (°C) | 37.38 ± 0.962 | 37.40 ± 1.164 | 0.272 |
| Fever (>38 °C) | 6/8 | 16/30 | 0.524 |
| Heart Rate (>160 beats/mins) | 3/11 | 3/43 | 0.139 |
| Respiratory Rate (>60/mins) | 4/10 | 8/38 | 0.453 |
| Capillary Refill (<3/<2 s) | 12/2 | 21/25 | 0.013 |
| Feeding Difficulties (Yes/No) | 4/10 | 22/24 | 0.227 |
| Leukocytes counts (<5×103/uL) | 1/13 | 0/46 | 0.237 |
| Platelets (<100×103/uL) | 5/9 | 5/41 | 0.047 |
| Blood glucose (<2.5 mmol/L) | 0/14 | 3/43 | 0.999 |
| RR (cpm) | 49.0 (42.0–66.50) | 46.0 (38.0–56.0) | 0.254 |
LCS-Laboratory confirmed sepsis; CS-Clinically confirmed sepsis; P-value<0.05 = statistically significant, Hb = Hemoglobin, WBC = White blood cell count, hs-CRP = High-sensitive C-reactive protein, sCD14-ST = presepsin, PCT = Procalicitonin, RR = Respiratory rate. P-value <0.05 was considered statistically significant (P-value of significant variable are in bold print).