Table 3.
Diagnostic Performance of biomarkers in the diagnosis of sepsis.
| Biomarker | Cut off | Sensitivity (95% CI) | Specificity (95% CI) | NPV (%) | PPV (%) | TP | TN | FP | FN | Jmax |
|---|---|---|---|---|---|---|---|---|---|---|
| Procalcitonin | 1.57 ng/ml | 57.14 (32.60–8.51) | 86.96 (73.84–94.16) | 57.14 | 86.96 | 8 | 40 | 6 | 6 | 0.44 |
| hs-C-Reactive Protein | 26.92 μg/L | 71.43 (44.89–88.44) | 86.96 (73.84–94.16) | 62.5 | 90.91 | 10 | 40 | 6 | 4 | 0.58 |
| sCD14 | 28.05 μg/L,m | 71.43 (44.89–88.44) | 76.09 (61.84–86.16) | 47.62 | 89.74 | 10 | 35 | 11 | 4 | 0.48 |
P-value<0.05 = statistically significant, sCD14-ST = presepsin, Jmax = Youden index, CI = Confidence Interval, NPV = Negative Predicted Value, PPV = Positive Predicted Value, TP = True Positive, TN = True Negative, FP = False Positive, FN = False Negative.