Table 4.

The diagnostic performance of Bioscore models using multiple logistic regression analysis in the diagnosis of sepsis.

Bioscore	Sensitivity (95% CI)	Specificity (95% CI)	NPV (%)	PPV (%)	TP	TN	FP	FN
CRP + PCT
0	71.43 (44.89–88.44)	86.96 (73.84–94.16)	90.91	62.5	10	40	6	4
1	57.14 (32.60–78.51)	86.96 (73.84–94.16)	86.96	57.14	8	40	6	6
2	0.0 (0.0–25.63)	100 (90.57–100.0)	76.37			46		14
CRP + sCD14
0	71.43 (44.89–88.44)	78.26 (64.16–87.84)	90	50	10	36	10	4
1	64.29 (38.59–83.63)	86.96 (73.84–94.16)	88.89	60	9	40	6	5
2	0.0 (0.0–25.63)	100 (90.57–100.0)	76.67			46		14
PCT + sCD14
0	83.33 (41.60–98.40)	70.37 (57.06–80.87)	97.44	23.81	5	3	16	1
1	83.33 (41.60–98.40)	77.78 (64.85–86.87)	91.3	14.29	2	42	12	4
2	0.0 (0.0–44.79)	100 (92.86–100)	90			54		6
CRP + sCD14+PCT
0	71.43 (44.89–88.44)	76.09 (61.84–86.16)	89.4	47.62	10	35	11	4
1	71.43 (44.89–88.44)	86.96 (73.84–94.16)	90.91	62.5	10	40	6	4
2	57.14 (32.60–78.51)	86.96 (73.84–94.16)	86.96	57.14	8	40	6	6
3	0.0 (0.0–25.63)	100 (90.57–100)	76.67				46	14

P-value<0.05 = statistically significant, sCD14-ST = presepsin, CRP = C-reactive Protein, PCT = Procalcltonin, CI = Confidence Interval, NPV = Negative Predicted Value, PPV = Positive Predicted Value, TP = True Positive, TN = True Negative, FP = False Positive, FN = False Negative.