TABLE 2.
Patient demographics
| Multicenter adult |
Single-center adult |
|||||
|---|---|---|---|---|---|---|
| Patients | No rejection n = 59 | Rejection n = 56 | P-value | No rejection n = 21 | Rejection n = 42 | P-value |
| Age (y), mean ± SD | 52 ± 11 | 51 ± 11 | .43 | 50 ± 14 | 50 ± 12 | .91 |
| Sex (male), n (%) | 47 (80) | 46 (82) | .82 | 15 (71) | 29 (69) | .99 |
| Race | ||||||
| White, n (%) | 37 (63) | 46 (82) | .04 | 12 (57) | 25 (60) | .06 |
| End-stage disease, n (%) | ||||||
| Idiopathic cardiomyopathy | 25 (42) | 28 (50) | .27 | 7 (33) | 15 (36) | .99 |
| Coronary artery disease | 12 (20) | 14 (25) | 0 | 1 (2) | ||
| Congenital heart disease | 0 (0) | 1 (2) | 2 (10) | 3 (7) | ||
| Myocarditis | 0 (0) | 1 (2) | 0 | 1 (2) | ||
| Valvular heart disease | 1 (2) | 0 (0) | 0 | 0 | ||
| Other etiology | 21 (36) | 12 (21) | 12 (57) | 22 (52) | ||
| Induction therapy, n (%) | 15 (25) | 19 (34) | .41 | 5 (24) | 11 (26) | .73 |
| Mechanical circulatory support, n (%) | 14 (24) | 15 (27) | .08 | 9 (43) | 11 (26) | .25 |
| HLA-A, -B, -DR mismatches ≥3, n/total (%) | 53/55 (96) | 45/48 (94) | .66 | 20/21 (95) | 42/42 (100) | .44 |