TABLE 4.
Non-HLA antibodies significantly associated with cardiac allograft rejection
| Gene symbol | Gene name | Cellular localization | Originally described in | Reference |
|---|---|---|---|---|
| EMCN | Endomucin | Plasma membrane and cytosol | Heart | a |
| DEXI | Dexamethasone induced transcript | Plasma membrane and cytosol | Heart | a |
| LPHN1 | Latrophilin 1 | Plasma membrane | Heart | a |
| SSB | Sjogren syndrome antigen B (autoantigen La) | Nucleus | Heart | a |
| Myosin | Myosin | Cytoskeleton | Heart | 46,47 |
| VIM | Vimentin | Cytoskeleton | Heart | 12 |
| Actin | Actin | Cytoskeleton | Heart | 48 |
| KRT8 | Cytokeratin 8 | Cytoskeleton | Heart | 48 |
| KRT18 | Cytokeratin 18 | Cytoskeleton | Heart | 48 |
| TUBα1b | Tubulin, α1b | Cytoskeleton | Heart | 33 |
| GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | Plasma membrane and cytosol | Heart | 36 |
| AGRN | Agrin | Plasma membrane and cytosol | Kidney | 34 |
| ENO1 | Alpha-enolase | Plasma membrane and cytosol | Kidney | 39 |
| PECR | Peroxisomal trans-2-enoyl-CoA reductase | Peroxisomes | Kidney | 35 |
| IL-21 | Integrin 21 | Secreted | Kidney | 51 |
| CXCL11 | Chemokine (C-X-C motif) ligand 11 | Secreted | Kidney | 51 |
| PRKC | Protein kinase C | Secreted | Kidney | 37 |
| FLT3LG | Fms-like tyrosine kinase-3 ligand | Intracellular and plasma membrane | Kidney | 23 |
a
Newly described here.